Course Outline

CHM311 Medicinal Organic Chemistry

Course Coordinator:Trong Tran (ttran1@usc.edu.au) School:School of Science, Technology and Engineering

2023Semester 2

UniSC Sunshine Coast

UniSC Moreton Bay

Blended learning Most of your course is on campus but you may be able to do some components of this course online.

Please go to usc.edu.au for up to date information on the
teaching sessions and campuses where this course is usually offered.

What is this course about?

Description

Medicinal Organic Chemistry extends the concepts covered in CHM202 Organic Chemistry. The course includes biological stereochemistry, reactions of heteroaromatics, advanced analytical and spectroscopic techniques, pericyclic reactions, the retro-synthesis approach to target compounds and natural product chemistry for drug discovery. There will be special emphasis on examples relevant to the Graduate Medical Schools Admission Test. By the end of this course, you will have an advanced knowledge of organic reactions and designing of organic syntheses.

How will this course be delivered?

Activity Hours Beginning Week Frequency
Blended learning
Learning materials – Online learning materials 1hr Week 1 13 times
Tutorial/Workshop 1 – Fortnightly 1 hour on-campus tutorial 1hr Week 2 6 times
Laboratory 1 – Fortnightly 3 hour on-campus practical 3hrs Week 1 7 times

Course Topics

  • Heteroaromatics
  • Pericyclic Reactions
  • Retrosynthesis
  • Asymmetric Synthesis
  • Advanced Analytical and Spectroscopic Techniques
  • Natural Product Chemistry
  • Drug Discovery
  • Drug Design.

What level is this course?

300 Level (Graduate)

Demonstrating coherence and breadth or depth of knowledge and skills. Independent application of knowledge and skills in unfamiliar contexts. Meeting professional requirements and AQF descriptors for the degree. May require pre-requisites where discipline specific introductory or developing knowledge or skills is necessary. Normally undertaken in the third or fourth full-time study year of an undergraduate program.

What is the unit value of this course?

12 units

How does this course contribute to my learning?

Course Learning Outcomes On successful completion of this course, you should be able to... Graduate Qualities Completing these tasks successfully will contribute to you becoming...
1 Plan and conduct laboratory experiments Empowered
2 Apply and explain mechanisms and reactions in Organic Chemistry Knowledgeable

Am I eligible to enrol in this course?

Refer to the UniSC Glossary of terms for definitions of “pre-requisites, co-requisites and anti-requisites”.

Pre-requisites

CHM202

Co-requisites

Not applicable

Anti-requisites

Not applicable

Specific assumed prior knowledge and skills (where applicable)

You must have an introductory knowledge of Organic Chemistry

How am I going to be assessed?

Grading Scale

Standard Grading (GRD)

High Distinction (HD), Distinction (DN), Credit (CR), Pass (PS), Fail (FL).

Details of early feedback on progress

In week 4, your tutorial participation and progress with understanding the chemical concepts will be informally assessed, and the opportunity given for student feedback.

Assessment tasks

Delivery mode Task No. Assessment Product Individual or Group Weighting % What is the duration / length? When should I submit? Where should I submit it?
All 1 Practical / Laboratory Skills Individual 40%
4x 500 - 800 words
Refer to Format To Supervisor
All 2 Examination - not Centrally Scheduled Individual 20%
1 hour, 800 words
Refer to Format In Class
All 3 Examination - Centrally Scheduled Individual 40%
2 hours, 1000 words
Exam Period Exam Venue
All - Assessment Task 1:Laboratory reports and assignment
Goal:
Laboratory skills are an essential of organic chemistry. The laboratory classes develop practical skills in planning and conducting experiments safely. Report writing is extended.
Product: Practical / Laboratory Skills
Format:
Submit: 3 lab reports 1 in weeks 7, 9 and 13, and a synthetic design assignment in week 11. Standard Scientific Report Title, Abstract, Experimental Procedure, Discussion, References
Criteria:
No. Learning Outcome assessed
1
Demonstration of good laboratory technique assessed by the laboratory supervisor, clear and concise scientific communication in the report.
1 2
All - Assessment Task 2:Mid semester exam
Goal:
This exam will focus on theory and mechanism of organic reactions
Product: Examination - not Centrally Scheduled
Format:
Submit in week 8 in tutorial time. Individual written exam covering the first half of semester's work
Criteria:
No. Learning Outcome assessed
1
Correctly answering the questions on organic reactions and mechanisms
2
All - Assessment Task 3:Final exam
Goal:
Demonstrate and apply knowledge of organic mechanisms and reactions
Product: Examination - Centrally Scheduled
Format:
Individual examination during central exam period
Criteria:
No. Learning Outcome assessed
1
​Correctly answering questions on organic mechanisms and reactivity​
1 2

Directed study hours

A 12-unit course will have total of 150 learning hours which will include directed study hours (including online if required), self-directed learning and completion of assessable tasks. Student workload is calculated at 12.5 learning hours per one unit.

What resources do I need to undertake this course?

Please note: Course information, including specific information of recommended readings, learning activities, resources, weekly readings, etc. are available on the course Canvas site– Please log in as soon as possible.

Prescribed text(s) or course reader

Please note that you need to have regular access to the resource(s) listed below. Resources may be required or recommended.

Required? Author Year Title Edition Publisher
Required Paula Yurkanis Bruice 2016 Organic Chemistry, Global Edition 8th n/a
Recommended Graham L. Patrick 2013 An Introduction to Medicinal Chemistry 5 Oxford University Press

Specific requirements

Safety glasses, laboratory coat and covered shoes must be brought to laboratory classes

How are risks managed in this course?

Risk assessments have been performed for all laboratory classes and a moderate level of health and safety risk exists. Moderate risks are those associated with laboratory work such as working with chemicals and hazardous substances. You will be required to undertake laboratory induction training and it is also your responsibility to review course material, search online, discuss with lecturers and peers and understand the health and safety risks associated with your specific course of study and to familiarise yourself with the University’s general health and safety principles by reviewing the online induction training for students, and following the instructions of the University staff

What administrative information is relevant to this course?

Assessment: Academic Integrity

Academic integrity is the ethical standard of university participation.  It ensures that students graduate as a result of proving they are competent in their discipline.  This is integral in maintaining the value of academic qualifications. Each industry has expectations and standards of the skills and knowledge within that discipline and these are reflected in assessment.

Academic integrity means that you do not engage in any activity that is considered to be academic fraud; including plagiarism, collusion or outsourcing any part of any assessment item to any other person.  You are expected to be honest and ethical by completing all work yourself and indicating in your work which ideas and information were developed by you and which were taken from others. You cannot provide your assessment work to others. You are also expected to provide evidence of wide and critical reading, usually by using appropriate academic references.

In order to minimise incidents of academic fraud, this course may require that some of its assessment tasks, when submitted to Canvas, are electronically checked through Turnitin.  This software allows for text comparisons to be made between your submitted assessment item and all other work to which Turnitin has access.

Assessment: Additional Requirements

Eligibility for Supplementary Assessment

Your eligibility for supplementary assessment in a course is dependent of the following conditions applying:

The final mark is in the percentage range 47% to 49.4%
The course is graded using the Standard Grading scale
You have not failed an assessment task in the course due to academic misconduct

Assessment: Submission penalties

Late submission of assessment tasks may be penalised at the following maximum rate (the rates are cumulative): 
- 5% (of the assessment task's identified value) per day for the first two days from the date identified as the due date for the assessment task. 
- 10% (of the assessment task's identified value) for the third day 
- 20% (of the assessment task's identified value) for the fourth day and subsequent days up to and including seven days from the date identified as the due date for the assessment task. 
- A result of zero is awarded for an assessment task submitted after seven days from the date identified as the due date for the assessment task. 
Weekdays and weekends are included in the calculation of days late. 
To request an extension you must contact your course coordinator to negotiate an outcome.

SafeUniSC

UniSC is committed to a culture of respect and providing a safe and supportive environment for all members of our community. For immediate assistance on campus contact SafeUniSC by phone: 07 5430 1168 or using the SafeZone app. For general enquires contact the SafeUniSC team by phone 07 5456 3864 or email safe@usc.edu.au.

The SafeUniSC Specialist Service is a Student Wellbeing service that provides free and confidential support to students who may have experienced or observed behaviour that could cause fear, offence or trauma. To contact the service call 07 5430 1226 or email studentwellbeing@usc.edu.au.

Study help

For help with course-specific advice, for example what information to include in your assessment, you should first contact your tutor, then your course coordinator, if needed.

If you require additional assistance, the Learning Advisers are trained professionals who are ready to help you develop a wide range of academic skills. Visit the Learning Advisers web page for more information, or contact Student Central for further assistance: +61 7 5430 2890 or studentcentral@usc.edu.au.

Wellbeing Services

Student Wellbeing provide free and confidential counselling on a wide range of personal, academic, social and psychological matters, to foster positive mental health and wellbeing for your academic success.

To book a confidential appointment go to Student Hub, email studentwellbeing@usc.edu.au or call 07 5430 1226.

AccessAbility Services

Ability Advisers ensure equal access to all aspects of university life. If your studies are affected by a disability, learning disorder mental health issue, injury or illness, or you are a primary carer for someone with a disability or who is considered frail and aged, AccessAbility Services can provide access to appropriate reasonable adjustments and practical advice about the support and facilities available to you throughout the University.

To book a confidential appointment go to Student Hub, email AccessAbility@usc.edu.au or call 07 5430 2890.

Links to relevant University policy and procedures

For more information on Academic Learning & Teaching categories including:

  • Assessment: Courses and Coursework Programs
  • Review of Assessment and Final Grades
  • Supplementary Assessment
  • Central Examinations
  • Deferred Examinations
  • Student Conduct
  • Students with a Disability

For more information, visit https://www.usc.edu.au/explore/policies-and-procedures#academic-learning-and-teaching

Student Charter

UniSC is committed to excellence in teaching, research and engagement in an environment that is inclusive, inspiring, safe and respectful. The Student Charter sets out what students can expect from the University, and what in turn is expected of students, to achieve these outcomes.

General Enquiries

  • In person:
    • UniSC Sunshine Coast - Student Central, Ground Floor, Building C, 90 Sippy Downs Drive, Sippy Downs
    • UniSC Moreton Bay - Service Centre, Ground Floor, Foundation Building, Gympie Road, Petrie
    • UniSC SouthBank - Student Central, Building A4 (SW1), 52 Merivale Street, South Brisbane
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  • Tel:+61 7 5430 2890
  • Email:studentcentral@usc.edu.au