Course Outline

MBT355 Bioinformatics

Course Coordinator:Renfu Shao (rshao@usc.edu.au) School:School of Science, Technology and Engineering

2026Trimester 1

UniSC Sunshine Coast

UniSC Moreton Bay

Blended learning Most of your course is on campus but you may be able to do some components of this course online.

Please go to unisc.edu.au for up to date information on the
teaching sessions and campuses where this course is usually offered.

What is this course about?

Description

This course will introduce you the principles and key concepts of bioinformatics and will start with basics about DNA, RNA and protein, then progress to databases, sequence alignments, evolutionary history reconstruction, genome annotation, and analysis of gene and protein expression. Systems biology, linux system and programming will also be introduced. Computer-based labs will provide you hands-on experience with databases and bioinformatics tools, and develop your skills in the analysis of biological data.

How will this course be delivered?

Activity Hours Beginning Week Frequency
Blended learning
Learning materials – The learning materials will introduce you the principles and key concepts of bioinformatics. Your will review the basics about DNA, RNA and protein, then progress to databases, sequence alignments, evolutionary history reconstruction, genome annotation, and analysis of gene and protein expression. Systems biology, linux system and programming will also be introduced. 2hrs Week 1 12 times
Laboratory 1 – Computer-based lab practicals will provide you hands-on experience with databases and bioinformatics tools, and develop your skills in the analysis of biological data. 2hrs Week 1 12 times
Seminar – These seminars will guide students to revise course learning materials and prepare for the end of trimester exam. 1hr Week 1 3 times

Course Topics

Bioinformatics, sequence, structure, database, genomics, transcriptomics, systems biology, programming

What level is this course?

300 Level (Graduate)

Demonstrating coherence and breadth or depth of knowledge and skills. Independent application of knowledge and skills in unfamiliar contexts. Meeting professional requirements and AQF descriptors for the degree. May require pre-requisites where discipline specific introductory or developing knowledge or skills is necessary. Normally undertaken in the third or fourth full-time study year of an undergraduate program.

What is the unit value of this course?

12 units

How does this course contribute to my learning?

Course Learning Outcomes On successful completion of this course, you should be able to... Graduate Qualities Completing these tasks successfully will contribute to you becoming...
1 Explain and describe the principles and key concepts of bioinformatics. Knowledgeable
2 Critically analyse how bioinformatics is used to make discoveries in biological sciences. Creative and critical thinker
3 Develop skills in literature review, database search, and the use of bioinformatics tools to address questions in biology. Empowered
4 Demonstrate skills to communicate scientific ideas to a variety of audiences regarding concepts in bioinformatics. Empowered

Am I eligible to enrol in this course?

Refer to the UniSC Glossary of terms for definitions of “pre-requisites, co-requisites and anti-requisites”.

Pre-requisites

LFS252 or SCI212 or BIM202

Co-requisites

Not applicable

Anti-requisites

Not applicable

Specific assumed prior knowledge and skills (where applicable)

Basic knowledge in genetics and molecular biology and basic computer skills

Microcredential Information

Not applicable

How am I going to be assessed?

Grading Scale

Standard Grading (GRD)

High Distinction (HD), Distinction (DN), Credit (CR), Pass (PS), Fail (FL).

Details of early feedback on progress

Early feedback will be provided in Weeks 1-4 in the practical reports. 

Assessment tasks

Delivery mode Task No. Assessment Product Individual or Group Weighting % What is the duration / length? When should I submit? Where should I submit it?
All 1 Report Individual 35%
150 words
Throughout teaching period (refer to Format) Online Submission
All 2 Essay Individual 30%
2000 words
Week 12 Online Assignment Submission with plagiarism check
All 3 Examination - Centrally Scheduled Individual 35%
2 hours
Exam Period Exam Venue
All - Assessment Task 1:Practical reports
Goal:
This task is designed to assist you to develop your conceptual understanding and practical skills in bioinformatics. You will use bioinformatics tools to address questions in biology.
Product: Report
Authorship Statement:
Format:
There are weekly practical activities in this course. Each practical comprises a set of short-answer questions. You are required to submit a report to answer the questions from each practical. Submit each report electronically in the following week after you undertake the practical.
Criteria:
No. Learning Outcome assessed
1
Completeness of all reports
1
2
Explanations and descriptions
2
3
Application of bioinformatics tools
3
Generic Skills:
Communication, Collaboration, Problem solving, Organisation, Applying technologies, Information literacy
All - Assessment Task 2:Essay
Goal:
To develop research and writing skills and in-depth understanding of scientific literature on a chosen bioinformatics tool and its use in biological discoveries.
Product: Essay
Authorship Statement:
Format:
You are required to submit an essay developed from your research concerning a bioinformatics tool of your choice. Search and review the literature published in peer-reviewed journals such as Bioinformatics, Genome Research, Molecular Biology and Evolution, Nucleic Acids Research, etc. Limit your essay to 2,000 words (excluding figures, tables, references and appendixes). Your essay must cover the following four aspects:1. Introduction of your chosen bioinformatics tool. Include information such as who developed the tool, what the tool is for, where the tool was published, how users can access this tool, who used the tool, etc. (20%)2. Principles and rationale of your chosen bioinformatics tool. Explain how the tool is designed (30%)3. Use of the bioinformatics tool in biological research. Explain what questions the bioinformatics tool has been used to address. Provide at least two examples in which the tool has facilitated discoveries. (40%)4. Future improvement of the tool. Offer your opinions and comments how the tool may be improved. (10%) Submit your essay electronically to Canvas - Turnitin before 5 pm, Friday, in Week 12 unless you have won an extension by completing the weekly online quizzes and short-answer questions. You will get 1-day extension for submission if you complete all of the online quizzes, and an additional 1-day extension if you complete all of the online short-answer questions. Furthermore, if your total score from the online quizzes and short-answer questions is 165 or above, you will get an extra 1-day extension.
Criteria:
No. Learning Outcome assessed
1
Description of the chosen bioinformatics tool
1
2
Explanation of the principles and rationale of the tool
2
3
Application of the tool
3
4
Appropriate selection of academic literature.
2
5
Critique of the literature
2
6
Critical analysis of the tool
2
7
Communication and use of references
4
Generic Skills:
Communication, Problem solving, Organisation, Applying technologies, Information literacy
All - Assessment Task 3:End of trimester exam
Goal:
 
Product: Examination - Centrally Scheduled
Authorship Statement:
Format:
You will sit a 2-hour exam based on the learning materials given in the course. The exam will be held under official exam conditions in a centralised exam venue. The exam will comprise multiple choice and short-answer questions. Online quizzes and short-answer questions will be provided from each week's learning materials to help you prepare the end of trimester exam. You are strongly encouraged to complete all of the online quizzes and short-answer questions.
Criteria:
No. Learning Outcome assessed
1
Knowledge, explanations and descriptions of bioinformatics concepts and principles.
1
2
Critical analysis of how bioinformatics is used to make discoveries in biological sciences.
2
3
Communication of scientific ideas to a variety of audiences regarding concepts in bioinformatics
3
Generic Skills:
Communication, Problem solving, Organisation, Information literacy

Directed study hours

A 12-unit course will have total of 150 learning hours which will include directed study hours (including online if required), self-directed learning and completion of assessable tasks. Student workload is calculated at 12.5 learning hours per one unit.

Schedule

Period and Topic Activities
Week 1 Course introduction; DNA, RNA and protein
Learning materials, Computer lab practical
Week 2 DNA sequencing technology, data generation and quality assessment
Learning materials, Computer lab practical
Week 3 Molecular biology databases
Learning materials, Computer lab practical
Week 4 Sequence alignment
Learning materials, Computer lab practical
Week 5 Revealing genome features
Learning materials, Computer lab practical
Week 6 Human genome analysis
Learning materials, Computer lab practical
Week 7 Protein secondary structure
Learning materials, Computer lab practical
Week 8 Protein tertiary structures
Learning materials, Computer lab practical
Week 9 Protein - from structure to function
Learning materials, Computer lab practical
Week 10 Gene and protein expression analysis
Learning materials, Computer lab practical
Week 11 Systems biology
Learning materials, Computer lab practical
Week 12 Linux system and programming
Learning materials, Computer lab practical
Week 13 Revision and exam prep
Seminar

What resources do I need to undertake this course?

Please note: Course information, including specific information of recommended readings, learning activities, resources, weekly readings, etc. are available on the course Canvas site– Please log in as soon as possible.

Prescribed text(s) or course reader

You need regular access to the resource(s) below. Many texts are available as ebooks through the Library at no additional cost.

Required? Author Year Title Edition Publisher
Recommended Marketa J. Zvelebil,Marketa J (The Institute of Cancer Research Zvelebil, UK),Marketa Zvelebil,Jeremy O. Baum,Jeremy O.. Baum 2008 Understanding Bioinformatics 1st Garland Science

Specific requirements

Nil

How are risks managed in this course?

Risk assessments have been performed for all studio and laboratory classes and a low level of health and safety risk exists. Some risk concerns may include equipment, instruments, and tools; as well as manual handling items within the laboratory. It is your responsibility to review course material, search online, discuss with lecturers and peers and understand the risks associated with your specific course of study and to familiarise yourself with the University’s general health and safety principles by reviewing the online induction training for students, and following the instructions of the University staff.

What administrative information is relevant to this course?

Assessment: Academic Integrity

Academic integrity is the ethical standard of university participation. It ensures that students graduate as a result of proving they are competent in their discipline. This is integral in maintaining the value of academic qualifications. Each industry has expectations and standards of the skills and knowledge within that discipline and these are reflected in assessment.

Academic integrity means that you do not engage in any activity that is considered to be academic fraud; including plagiarism, collusion or outsourcing any part of any assessment item to any other person. You are expected to be honest and ethical by completing all work yourself and indicating in your work which ideas and information were developed by you and which were taken from others. You cannot provide your assessment work to others. You are also expected to provide evidence of wide and critical reading, usually by using appropriate academic references.

In order to minimise incidents of academic fraud, this course may require that some of its assessment tasks, when submitted to Canvas, are electronically checked through Turnitin. This software allows for text comparisons to be made between your submitted assessment item and all other work to which Turnitin has access.

Assessment: Additional Requirements

Eligibility for Supplementary Assessment

Your eligibility for supplementary assessment in a course is dependent of the following conditions applying:
(a) The final mark is in the percentage range 47% to 49.4%; and
(b) The course is graded using the Standard Grading scale

Eligibility for Supplementary Assessment Your eligibility for supplementary assessment in a course is dependent of the following conditions applying: The final mark is in the percentage range 47% to 49.4% The course is graded using the Standard Grading scale You have not failed an assessment task in the course due to academic misconduct

Assessment: Submission penalties

Late submissions may be penalised up to and including the following maximum percentage of the assessment task’s identified value, with weekdays and weekends included in the calculation of days late:
(a) One day: deduct 5%;
(b) Two days: deduct 10%;
(c) Three days: deduct 20%;
(d) Four days: deduct 40%;
(e) Five days: deduct 60%;
(f) Six days: deduct 80%;
(g) Seven days: A result of zero is awarded for the assessment task.

The following penalties will apply for a late submission for an online examination:
Less than 15 minutes: No penalty
From 15 minutes to 30 minutes: 20% penalty
More than 30 minutes: 100% penalty

Links to relevant University policy and procedures

For more information on Academic Learning & Teaching categories including:

  • Assessment: Courses and Coursework Programs
  • Review of Assessment and Final Grades
  • Supplementary Assessment
  • Central Examinations
  • Deferred Examinations
  • Student Conduct
  • Students with a Disability

For more information, visit https://www.usc.edu.au/explore/policies-and-procedures#academic-learning-and-teaching

Student Charter

UniSC is committed to excellence in teaching, research and engagement in an environment that is inclusive, inspiring, safe and respectful. The Student Charter sets out what students can expect from the University, and what in turn is expected of students, to achieve these outcomes.

General Enquiries

For course-specific questions, contact your teaching staff or Course Coordinator.  

For other enquiries or to access support, please contact Student Central: